Oct 24, 2018 The Radula compound has been dubbed perrottetinene, or PET, after Radula perrottetii, one of the few liverwort species that makes it. Although researchers first described perrottetinene in 1994. Turmeric and black peppper for inflation no sugar. Moms went away when she went in the “Candida diet” after months she had no pain or inflammation, don’t doubt Candida albicans, starts as a single cell yeast and grows threads and connects togeather through your cells and becomes more like mycelium. Love the taste. Take with a glass of water (its easy on the stomach). Healthy feeling with no chemical feel. 180 lb taking two dropper fulls gives some body relaxation. Definitely going to use with the cbd hemp oil got coming, had cbd extract before. I know the combo is going to relax the muscle knots and deep nerve pain. Being a former truck driver the best combinations win. Grow A Plant for many reasons, it is our duty to save our environment & our future generations. We need fresh air, fruits, veggies & cereals to live happily & peacefully. Perrottetinene is a naturally occurring cannabinoid compound found in liverworts from the genus Radula native to Japan, New Zealand and Costa Rica, namely Radula perrottetii, Radula marginata and Radula laxiramea, along with a number of similar compounds. Its chemical structure closely resembles that of THC, the main active component of marijuana.The absolute configuration of perrottetinene.
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Radula marginata (Wairuakohu) is a species of plant in genus Radula[1], a genus of liverworts. It is endemic to New Zealand.[2][3] It has been found to contain cannabinoids.[4][5]
Cannabinoids[edit]
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Users smoking the plant have experienced different effects.[6][citation needed] The cannabinoid is not THC, the main psychoactive chemical in cannabis, but it is of similar molecular structure.[4] The liverwort contains perrottetinene and perrottetinenic acid.[4] The quantity of cannabinoid present is much less than in cannabis. Perrottetinene has been shown to be a moderately potent CB1 agonist leading to mild psychoactive effects in mice.[7]
Legal status[edit]
The liverwort grows as a common weed.[citation needed] Owning, growing and distributing the liverwort is legal.
Radula marginata may have been used in rongoā (Māori herbal medicine), but there is no firm evidence of this.
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References[edit]
- ^Hussain, Tajammul; Espley, Richard V.; Gertsch, Jürg; Whare, Tracey; Stehle, Felix; Kayser, Oliver (2019). 'Demystifying the liverwort Radula marginata, a critical review on its taxonomy, genetics, cannabinoid phytochemistry and pharmacology'. Phytochemistry Reviews. 18 (3): 953–965. doi:10.1007/s11101-019-09638-8.
- ^http://www.discoverlife.org/mp/20l?id=GBIF2550163
- ^http://www.discoverlife.org/mp/20l?id=GBIF2550057
- ^ abcToyota, M.; et al. (2002). 'New bibenzyl cannabinoid from the New Zealand liverwort Radula marginata'(PDF). Chem Pharm Bull. 50 (10): 1390. doi:10.1248/cpb.50.1390.
- ^Hussain, Tajammul; Plunkett, Blue; Ejaz, Mahwish; Espley, Richard V.; Kayser, Oliver (2018). 'Identification of Putative Precursor Genes for the Biosynthesis of Cannabinoid-Like Compound in Radula marginata'. Frontiers in Plant Science. 9: 537. doi:10.3389/fpls.2018.00537. PMC5954354. PMID29868043.
- ^http://www.tripme.co.nz/forums/showthread.php?t=1943
- ^Chicca, A.; Schafroth, M. A.; Reynoso-Moreno, I.; Erni, R.; Petrucci, V.; Carreira, E. M.; Gertsch, J. (1 October 2018). 'Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high'. Science Advances. 4 (10): eaat2166. doi:10.1126/sciadv.aat2166. ISSN2375-2548. PMC6200358. PMID30397641.
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